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Atrial fibrosis is an essential feature of atrial structural remodeling, driven by factors that stimulate fibroblast proliferation and differentiation into myofibroblasts, resulting in excessive extracellular matrix (ECM) production

Understanding Laser Treatment for Acne Scars Laser treatments work by delivering controlled energy into the skin to stimulate collagen production and resurface damaged layers

Because of the lack of a control group and the open-label study design, a placebo effect secondary to the surgical procedure, DBS adjustment, and continuous follow-up cannot be excluded to confirm the accurate efficacy of DBS treatment

The comparison highlights the enormous evidence gap between a fully validated drug and a promising preclinical compound